Research projects

Research and innovation are fundamental pillars of the Reus Lipid Cluster. Through competitive national and international funding programs, the cluster promotes collaborative research projects focused on advancing knowledge in lipid metabolism, cardiovascular health, precision medicine, and biomedical technologies. These initiatives strengthen collaboration between academia, healthcare institutions, and industry, while accelerating the translation of scientific discoveries into clinical and real-world applications.

Below are some of the latest research projects awarded through competitive funding calls, reflecting the cluster’s strong commitment to scientific excellence and innovation.

TB-OMICS Project:  25 October 2025

Funding obtained under the CPP2024 Public-Private Partnership Projects call for the development of the TB-OMICS project, “Innovative software for tuberculosis diagnosis based on specific urinary biomarkers (CPP2024-011551), aimed at developing and validating an innovative diagnostic solution for tuberculosis (TB). The project is based on the identification of specific metabolomic biomarkers in urine samples using low-field Nuclear Magnetic Resonance (NMR) technology combined with advanced computational analysis and artificial intelligence tools. Coordinator: Biosfer Teslab

Carlos III Health Research Call Project: 27 December 2024 

A panel of non-cholesterol-related lipoprotein biomarkers for the early detection of rapid atherosclerosis progression in subjects with normal LDL cholesterol: This project aims to identify a novel panel of non-conventional lipoprotein biomarkers for the early detection of rapid atherosclerosis progression in individuals with normal LDL cholesterol levels. Led by PI Josep Ribalta and Montse Guardiola and funded by ISCIII, the study combines advanced lipoprotein profiling with classical cardiovascular risk factors to improve the identification of high-risk subjects within the ILERVAS cohort (n=1300).

DALÍ Project: 17 December 2024 

Funding was obtained under the CDTI International Technological Cooperation R&D Projects – Multinational Programme for the development of the DALÍ project (PAIS-202441060), focused on the research and validation of an innovative colorectal cancer screening test based on metabolomics technologies using Nuclear Magnetic Resonance (NMR). The project aims to identify metabolic biomarkers for earlier and less invasive detection of colorectal cancer, facilitating the future implementation of this technology in routine clinical practice and improving current screening strategies.Coordinator: Biosfer Teslab

 

COMPREMETE Project: 17 December 2024

Funding was obtained under the CDTI International Technological Cooperation R&D Projects – Multinational Programme for the development of the COMPREMETE project (PAIS-20241010), focused on the research and validation of an advanced screening tool for the early detection of preterm birth risk, based on the integration of metabolomics and electrohysterography technologies, supporting the future implementation of non-invasive diagnostic strategies in routine prenatal care. Coordinator: Biosfer Teslab

 

GALVANO Project: 24 October 2024

Funding was obtained under the 2023 Public-Private Partnership Projects call, funded by the Spanish Ministry of Science and Innovation and the State Research Agency, for the development of the GALVANO project – “Optimization, Validation and Exploitation of a Versatile Clinical-Grade Extracellular Vesicle Production Platform through Process Analytical Technology” (CPP2023-010430). The project focuses on improving and validating scalable production processes for clinical-grade extracellular vesicles, with the objective of facilitating their future application in advanced therapies and precision medicine. Collaborator: Biosfer Teslab

HARMONi Project: 27 October 2023

Funding was obtained under the 2022 Public-Private Partnership Projects call, funded by the Spanish Ministry of Science and Innovation and the State Research Agency, for the development of the HARMONi Project – HARnessing the power of MultiOmics: towards the generation of Novel & Innovative diagnostic tools to improve cardiovascular risk prediction (CPP2022-010039). The project focuses on the integration of multi-omics technologies to improve cardiovascular risk prediction through the development of innovative diagnostic tools and biomarker-based strategies, contributing to personalized and preventive medicine. Coordinator: Biosfer Teslab

INVESTIGO program: 27 April 2023

Two grants under the INVESTIGO program, part of the Recovery, Transformation, and Resilience Plan – funded by the European Union through NextGenerationEU – for the hiring of young people under 30 years old seeking employment, aimed at the development and execution of research and innovation functions, tasks, and initiatives, granted by AGAUR in 2023. These grants promoted youth employment in research and innovation and supported the participation of young talent in projects with scientific and social impact.

 

HORIZON.1.2 Program – Marie Sklodowska-Curie Actions (MSCA): 27 January 2023

With the CARDIOSCOPE project (2022): Comprehensive and personalized assessment of acute coronary syndrome through a multi-omic approach and artificial intelligence strategy (2022). The project focused on integrating multi-omic data and advanced artificial intelligence tools to improve the diagnosis, risk stratification, and personalized management of patients with acute coronary syndrome. It also aimed to enhance precision medicine approaches by identifying novel biomarkers and predictive models for cardiovascular disease outcomes.